12 Ways Peak Male Can Boost Your Manhood and Protect Your Health

Peak Male^® is much more than just a powerful men’s supplement. It’s also formulated to protect your health in ways no other men’s supplement does -- including every T booster out there.^* The true power behind the Peak Male formula is that it safely works to bring your body into balance.^*

As a premium supplement (at about ½ the cost and 10x the benefits of the best options available), Peak Male optimizes a man’s hormones, providing numerous scientifically proven benefits (see below).*

Scientifically Formulated with Adaptogen Herbs to Protect Your Health

Many of Peak Male’s unique patent-pending formula’s active ingredients are “adaptogenic” herbs. Studies show that adaptogens protect your health and rejuvenate your entire body by helping you resist and overcome the ravages of every type of STRESS while restoring your energy, strength, stamina, and vitality.*

Here are some of the amazing benefits that the herbs in Peak Male have been proven to provide:

Strengthens Your Immunity

The adaptogen herbs in Peak Male strengthen your immunity in two very important ways. First, they combat stress and protect your body from the serious harm stress can cause to your immune system.^1,2,* Hundreds of studies show that colds, flu, and infections of all types are directly linked to chronic stress -- and adaptogens have been proven to help your body resist stress and the damage it can cause.*

The second way Peak Male’s adaptogens strengthen your immunity is by directly stimulating the production of some of the most powerful immunity cells in our body -- cells that destroy foreign invaders.* These cells include 1, * white blood cells (T lymphocytes and B lymphocytes) which fight infections, and 2, * natural killer (NK) cells, which are one of your body’s most powerful defenders against deadly diseases.* In addition, the adaptogen herbs in Peak Male increase interleukin 2 * and strengthen the immune system’s response to viruses (and even much worse).*

Boosts Metabolism & Burns Fat

Peak Male’s powerful blend of natural herbs is designed to boost your metabolism and increase fat burning, especially targeting the dangerous visceral fat that surrounds your organs. Peak Male is specially formulated to optimize the master metabolic switch in your body (known as “AMPK”).

If your metabolism is sluggish and not burning fat at an optimal level, your metabolic switch may be “turned off.” Our patent-pending formula contains a proprietary herbal blend, Metabo-Burn^®, designed to flip your metabolic switch on and jump-start your metabolism.^{5, *}

Increased Energy, & Vitality & Less Fatigue

Peak Male supports long-lasting, sustained energy at the cellular, mitochondria level. Mitochondria are often referred to as the “powerhouses of the cell” because they are responsible for ATP production (adenosine triphosphate), which is the chemical energy cells need to survive. No energy = no life, so the importance of ATP in your body cannot be overstated.

Peak Male’s unique combination of adaptogenic herbs helps your mitochondria function at an optimal level and pump out healthy amounts of ATP, which reduces fatigue and keeps your body energized all day long with none of the jitters of stimulants.^{6, 7, *}

Muscle, Strength, Endurance, & Recovery

Regardless of your age, Peak Male is specially designed to help your body reach a regenerative (anabolic) phase. Peak Male contains a synergistic proprietary blend called MAX T-Booster^TM, which works in combination with other supportive herbs designed to increase protein synthesis and support your most important “building” hormones, including your T levels, DHEA, thyroid hormone, and others.

Hundreds of studies show that the herbs in the MAX T-Booster formula increase muscle strength and size, endurance and energy levels, and reduce muscle damage and inflammation -- all of which help to speed muscle recovery. At the same time, these herbs are increasing free T levels and decreasing body fat percentages.^{1, 24, *}

Powerful Stress & Anxiety Relief

Peak Male contains adaptogens -- nature’s most powerful anti-stress and anti-anxiety herbs -- which have been specifically formulated to reduce all types of stress and the damage they cause, as well as increase your resistance to stress.

Stressors hit us continuously in the form of short-term acute stress and long-term chronic stress. Whether the stressors come from toxins in food, drinks, medications, or the air we breathe -- or is mental stress from work, relationships, or financial issues -- or is physical stress from lack of sleep or too much exertion, they all have a cumulative effect that is damaging to the body in a multitude of different ways.

Peak Male’s adaptogen herbs protect you from the serious, life-shortening health dangers all of these stressors can cause.^{5, 6, 24, *}

Better Mood & Mental Clarity

Peak Male provides the perfect blend of time-tested, brain-boosting herbs that support healthy brain activity by specifically acting on the key neurotransmitters such as serotonin. These neuro-chemicals help improve mood, alleviate depression, increase mental and physical stamina, improve nervous system function, movement, endurance, and circulation, which is important for clear thinking and a healthy memory.

A second way Peak Male improves mental functioning is by relieving stress, which is often the reason we have “brain fog.” When stress is relieved, you can focus and concentrate much better, think more clearly, and enjoy a significant improvement in memory.^{7, *}

Sound, Restful Sleep

Recent research shows that sleep quality is mainly governed by stress and hormones. And these are two areas where Peak Male shines for you. Peak Male utilizes a combination of relaxing, anti-anxiety herbs shown to help people fall asleep and stay asleep and wake up feeling refreshed and energized. This important benefit has wide-reaching health benefits.

In fact, poor sleep can have detrimental effects on the entire body and contributes to many serious problems, including increased risk of cancer, heart disease, high blood pressure, diabetes, a weakened immune system (which exposes you to many other diseases), and a shortened lifespan.^{8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, *}

Circulation & Cardiovascular Health

Cardiovascular disease is the #1 killer disease of Americans today. A leading factor in cardiovascular health is nitric oxide (NO). NO is naturally produced in our cells and plays an important role in protecting against cardiovascular disease onset and progression. ⁽²⁸⁾ It is absolutely crucial to heart and blood vessel health. Increasing nitric oxide not only supports healthy blood flow and circulation by relaxing and dilating arteries and blood vessels, but it also stimulates the development of new blood vessels (angiogenesis) for healing.

Nitric oxide production tends to decline with age, which is why Peak Male was formulated with specific ingredients proven to boost NO, promote good circulation, and support cardiovascular health.*

Powerful Anti-Inflammatory, Pain Relieving Herbs

Studies show that Peak Male adaptogens have exceptional anti-inflammatory and pain-relieving properties. Extensive research has linked inflammation to nearly every modern disease.

Peak Male helps suppress chronic inflammation and supports a healthy inflammation response because the process of inflammation relies greatly on hormonal feedback. When this feedback is disrupted (by stress or metabolic syndrome), the immune system has trouble recognizing when and for how long to activate the inflammatory response. ⁽³⁾ This opens the door for numerous diseases.

Because Peak Male naturally helps your body balance hormone levels, your body can more easily respond to these normal physiological stages and prevent inflammation from becoming chronic.^{2, 4, 6, *}

Rich in Antioxidants

Peak Male is loaded with potent antioxidants. That’s because all adaptogens are powerful antioxidants; however, very few antioxidants are adaptogens.

Chronic oxidation in the body can cause inflammation and a host of other health problems, including advanced glycation end products (AGEs). AGEs are formed when protein or fat combine with sugar in the bloodstream, and they literally cause every part of your body to age, from your skin to your brain to your organs.

The powerful antioxidant effects of the herbs in Peak Male reduce oxidative stress and AGEs throughout the body, which reduces the inflammation and the catabolic breakdown they cause.^{25, 26, *}

“Clean House” at a Cellular Level & Rejuvenate You’re Whole Your Body

Peak Male helps you ‘clean house’ by attacking cellular-level “sludge.” This harmful, sludge-like buildup is accumulated through everyday life. It can cause a whole host of health problems, including low energy, lack of motivation, accelerated aging, mental fog, difficulty sleeping, depression, headaches, weight gain, hormonal imbalances, and more.

Peak Male works on the cellular level to clean out your entire body from your brain to your blood to your organs, to your hormone-regulating glands. Inner cleansing at this cellular level gets to the heart of the problem to strengthen and revitalize your whole body.^{27, *}

Complete Hormonal Rebalance (Not Just a Man’s T Levels)

Peak Male is leap-years ahead of even the highest quality and most expensive T-boosters available because it doesn’t just naturally and safely increase your T (including free T); it actually works to balance ALL your hormones.

Hormones regulate almost everything in your body, and when even one of them is too high or too low, health issues can arise, sometimes serious ones. There is a multitude of reasons why any of the 50+ hormones produced by the human body can get out of balance, and the longer the imbalance persists, the more problems can arise.

The herbs in Peak Male have been shown to be very effective in normalizing your hormone levels, which can bring your body back into optimal balance. ^{6, *}

Peak Male Product Details

Safe and Natural
No Harmful ingredients
No caffeine and no stimulants
All Natural Adaptogenic herbal formula
Servings per bottle: 30 (120 Capsules)
Satisfaction money-back guarantee
Manufactured in an FDA registered facility in the USA
Good Manufacturing Practices (GMP)
No soy, dairy, gluten, eggs, fish, shellfish, tree nuts, peanuts, or wheat

120-Day Money-Back Guarantee

We are confident you will be very happy with the results you gain from Peak Male. That’s why we offer the industry-leading 120-day satisfaction guarantee.

If, for any reason, you are not delighted with Peak Male, just return the unused portion or even empty bottles with your name and address within 120 days of your purchase date. Upon receipt, we will refund your purchase price, less shipping & handling within 24 hours of receiving your return (except on holidays and weekends). Refunds typically take an additional 3 to 4 business days to show on your credit card statement.

Adaptogens: the Stunning Soviet Discovery

lazyload

Adaptogens are ancient, natural herbs that come from a highly-researched specific type of plant that has developed properties to:

Adapt to the most extreme, harsh, and stressful environments on earth.

When ingested, scientists have discovered that these adaptogenic herbs pass their amazing ability to adapt to and overcome stress.
Adaptogens were used in ancient Chinese medicine by Viking Warriors, Siberian hunters, and other cultures to increase energy, strength, and mental and physical endurance before going on dangerous hunts, into battle, or on long, arduous journeys.^{1, *}
Adaptogens have also been used for centuries as a healer by many different Asian cultures who discovered they strengthen the body’s resistance to disease and have anti-fatigue, anti-anxiety, anti-inflammatory, anti-depression, and anti-aging characteristics.^{2, *}
In modern times, these herbs were rediscovered by Soviet scientists and given to their Olympic athletes, astronauts, elite soldiers, and even World Champion chess players because of their amazing ability to reduce stress and strengthen immunity coupled with their extraordinary physical and mental performance-boosting properties.

For more information about the modern use of adaptogens, go here: The Amazing Russian Discovery.

Lost 25 lbs!!

Peak Male has helped me lose over 25 pounds in the last three months. I have been losing around a pound a week, just doing my regular routine. I recommend this supplement to anyone that wants to lose some extra weight.*

--Joe P - Denver, CO

Many Different Great Results: Muscle, Sex Drive, Confidence, Energy, Sleep

Several things happened to me when I started taking Peak Male a couple of months ago. After about 4-6 weeks, I started seeing results: -I looked more muscular and leaner. My muscles felt fuller, and recovery after working out was AMAZING. -My sex drive did increase. I noticed a stronger blood flow down there. - I felt more stable emotionally, more confident, more of an “Alpha male.” I’ve been going through some hard times recently and have been pretty depressed, but this product noticeably stabilized my mood. - I’m having more energy at the gym. Also, I noticed that I could lift more weight and do higher reps with ease. - My sleep has been out of this world. In the first week, I was sleeping like a baby. It felt great to have a good night of sleep again. -I think this product will ultimately do more the longer I take it. I’m still a little hesitant, but I feel great for now!*

--Shaun L. - West Palm Beach, FL

Felt So Calm

I’m impressed. I got this product 3 days ago, and I’ve never had such a great result so quickly! I felt so calm. It’s different than any other herbal product I’ve ever tried. This is really good stuff!*

--Wilson R. - McKinney, TX

More Energy, Lifts More Weight, Lost Fat, Increased Muscle Size

I just started taking my second bottle of Peak Male, and I am really loving the results so far. After about 3 weeks, I started noticing increased energy and better sleep. I didn’t change my diet at all, but I have now lost 6 lbs, and in the gym, when I am lifting, I can do more reps and higher weight -- which is amazing to me because I’ve changed nothing other than using Peak Male. Also, I have never been able to get my arms to grow much from lifting, but they are actually getting bigger (both bi’s and tri’s), which I never thought possible. I am really looking forward to seeing what happens with my second bottle.*

--Jon P. - Ojai, CA

Not Feeling Sluggish Anymore, Upbeat Energy

I’m not feeling sluggish anymore, sleeping better, and my energy is upbeat and a nice balance with more focus.*

--Charles R - Tampa, FL

Leg Cramps Gone, Relaxed & Happy, More Sex Drive, Sleeps Like a Rock!

I’ve been taking Peak Male for about 3 months. I used to get cramps in my legs quite often, but ever since I started taking Peak Male, I haven’t gotten any cramps at all. Also, my wife and friends are asking what I am doing because they noticed that I am in a much better mood every day. I work long hours, so I used to get home in a bad mood every night. Not anymore, Peak Male is helping me stay more relaxed, and I feel happier every day. My sex drive has increased, so my wife is very happy about that! And I feel more energetic than before. I have a couple of kids that will get home after 10:00 pm, and every time they enter the house, they would wake me up. Not anymore! Ever since I started taking Peak Male, I sleep like a rock, and I don’t hear anyone come home. I am so happy with Peak male that I will be taking this product for a very long time!*

--Luis V - San Diego, CA

12 Ways Peak Male Can Boost Your Manhood and Protect Your Health

Peak Male® is much more than just a powerful men’s supplement. It’s also formulated to protect your health in ways no other men’s supplement does -- including every T booster out there.* The true power behind the Peak Male formula is that it safely works to bring your body into balance.*

As a premium supplement (at about ½ the cost and 10x the benefits of the best options available), Peak Male optimizes a man’s hormones providing an impressive number of scientifically-proven benefits (see below).*

Scientifically Formulated with Adaptogen Herbs to Protect Your Health

Many of Peak Male’s unique patent-pending formula’s active ingredients are “adaptogenic” herbs. Studies show that adaptogens protect your health and rejuvenate your entire body by helping you resist and overcome the ravages of every type of STRESS -- while also restoring your energy, strength, stamina, and vitality.*

Here are some of the amazing benefits that the herbs in Peak Male have been proven to provide:

Strengthens Your Immunity

The adaptogen herbs in Peak Male strengthen your immunity in two very important ways. First, they combat stress and protect your body from the serious harm stress can cause to your immune system.1,2,* Hundreds of studies show that colds, flu, and infections of all types are directly linked to chronic stress -- and adaptogens have been proven to help your body resist stress and the damage it can cause.*

The second way Peak Male’s adaptogens strengthen your immunity is by directly stimulating the production of some of the most powerful immunity cells in our body -- cells that destroy foreign invaders.* These cells include 1, * white blood cells (T lymphocytes and B lymphocytes) which fight infections, and 2, * natural killer (NK) cells, which are one of your body’s most powerful defenders against deadly diseases.* In addition, the adaptogen herbs in Peak Male increase interleukin 2, * and which strengthen the immune system’s response to viruses (and even much worse).*

Boosts Metabolism & Burns Fat

Peak Male’s powerful blend of natural herbs is designed to boost your metabolism and increase fat burning, especially targeting the dangerous visceral fat that surrounds your organs. Peak Male is specially formulated to optimize the master metabolic switch in your body (known as “AMPK”).

If your metabolism is sluggish and not burning fat at an optimal level, your metabolic switch may be “turned off.” Our patent-pending formula contains a proprietary herbal blend, Metabo-Burn®, designed to flip your metabolic switch on and jump-start your metabolism.5, *

Increased Energy, & Vitality & Less Fatigue

Peak Male supports long-lasting, sustained energy at the cellular, mitochondria level. Mitochondria are often referred to as the “powerhouses of the cell” because they are responsible for ATP production (adenosine triphosphate), which is the chemical energy cells need to survive. No energy = no life, so the importance of ATP in your body cannot be overstated.

Peak Male’s unique combination of adaptogenic herbs helps your mitochondria function at an optimal level and pump out healthy amounts of ATP, which reduces fatigue and keeps your body energized all day long with none of the jitters of stimulants.6, 7, *

Muscle, Strength, Endurance, & Recovery

Regardless of your age, Peak Male is specially designed to help your body reach a regenerative (anabolic) phase. Peak Male contains a synergistic proprietary blend called MAX T-BoosterTM, which works in combination with other supportive herbs designed to increase protein synthesis and support your most important “building” hormones, including your T levels, DHEA, thyroid hormone, and others.

Hundreds of studies show that the herbs in the MAX T-Booster formula increase muscle strength and size, endurance and energy levels, and reduce muscle damage and inflammation -- all of which help to speed muscle recovery. At the same time, these herbs are increasing free T levels and decreasing body fat percentages.1, 24, *

Powerful Stress & Anxiety Relief

Peak Male contains adaptogens -- nature’s most powerful anti-stress and anti-anxiety herbs -- which have been specifically formulated to reduce all types of stress and the damage they cause, as well as increase your resistance to stress.

Stressors hit us continuously in the form of short-term acute stress and long-term chronic stress. Whether the stressors come from toxins in food, drinks, medications, or the air we breathe -- or is mental stress from work, relationships, or financial issues -- or is physical stress from lack of sleep or too much exertion, they all have a cumulative effect that is damaging to the body in a multitude of different ways.

Peak Male’s adaptogen herbs protect you from the serious, life-shortening health dangers all of these stressors can cause.5, 6, 24, *

Better Mood & Mental Clarity

Peak Male provides the perfect blend of time-tested, brain-boosting herbs that support healthy brain activity by specifically acting on the key neurotransmitters such as serotonin. These neuro-chemicals help improve mood, alleviate depression, increase mental and physical stamina, improve nervous system function, movement, endurance, and circulation, which is important for clear thinking and a healthy memory.

A second way Peak Male improves mental functioning is by relieving stress, which is often the reason we have “brain fog.” When stress is relieved, you can focus and concentrate much better, think more clearly, and enjoy a significant improvement in memory.7, *

Sound, Restful Sleep

Recent research shows that sleep quality is mainly governed by stress and hormones. And these are two areas where Peak Male shines for you. Peak Male utilizes a combination of relaxing, anti-anxiety herbs shown to help people fall asleep and stay asleep and wake up feeling refreshed and energized. This important benefit has wide-reaching health benefits.

In fact, poor sleep can have detrimental effects on the entire body and contributes to many serious problems, including increased risk of cancer, heart disease, high blood pressure, diabetes, a weakened immune system (which exposes you to many other diseases), and a shortened lifespan.8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, *

Circulation & Cardiovascular Health

Cardiovascular disease is the #1 killer disease of Americans today. A leading factor in cardiovascular health is nitric oxide (NO). NO is naturally produced in our cells and plays an important role in protecting against cardiovascular disease onset and progression. (28) It is absolutely crucial to heart and blood vessel health. Increasing nitric oxide not only supports healthy blood flow and circulation by relaxing and dilating arteries and blood vessels, but it also stimulates the development of new blood vessels (angiogenesis) for healing.

Nitric oxide production tends to decline with age, which is why Peak Male was formulated with specific ingredients proven to boost NO, promote good circulation, and support cardiovascular health.*

Powerful Anti-Inflammatory, Pain Relieving Herbs

Studies show that Peak Male adaptogens have exceptional anti-inflammatory and pain-relieving properties. Extensive research has linked inflammation to nearly every modern disease.

Peak Male helps suppress chronic inflammation and supports a healthy inflammation response because the process of inflammation relies greatly on hormonal feedback. When this feedback is disrupted (by stress or metabolic syndrome), the immune system has trouble recognizing when and for how long to activate the inflammatory response. (3) This opens the door for numerous diseases.

Because Peak Male naturally helps your body balance hormone levels, your body can more easily respond to these normal physiological stages and prevent inflammation from becoming chronic.2, 4, 6, *

Rich in Antioxidants

Peak Male is loaded with potent antioxidants. That’s because all adaptogens are powerful antioxidants; however, very few antioxidants are adaptogens.

Chronic oxidation in the body can cause inflammation and a host of other health problems, including advanced glycation end products (AGEs). AGEs are formed when protein or fat combine with sugar in the bloodstream, and they literally cause every part of your body to age, from your skin to your brain to your organs.

The powerful antioxidant effects of the herbs in Peak Male reduce oxidative stress and AGEs throughout the body, which reduces the inflammation and the catabolic breakdown they cause.25, 26, *

“Clean House” at a Cellular Level & Rejuvenate You’re Whole Your Body

Peak Male helps you ‘clean house’ by attacking cellular-level “sludge.” This harmful, sludge-like buildup is accumulated through everyday life. It can cause a whole host of health problems, including low energy, lack of motivation, accelerated aging, mental fog, difficulty sleeping, depression, headaches, weight gain, hormonal imbalances, and more.

Peak Male works on the cellular level to clean out your entire body from your brain to your blood to your organs, to your hormone-regulating glands. Inner cleansing at this cellular level gets to the heart of the problem to strengthen and revitalize your whole body.27, *

Complete Hormonal Rebalance (Not Just a Man’s T Levels)

Peak Male is leap-years ahead of even the highest quality and most expensive T-boosters available because it doesn’t just naturally and safely increase your T (including free T); it actually works to balance ALL your hormones.

Hormones regulate almost everything in your body, and when even one of them is too high or too low, health issues can arise, sometimes serious ones. There is a multitude of reasons why any of the 50+ hormones produced by the human body can get out of balance, and the longer the imbalance persists, the more problems can arise.

The herbs in Peak Male have been shown to be very effective in normalizing your hormone levels, which can bring your body back into optimal balance. 6, *

Peak Male Product Details

Safe and Natural
No Harmful ingredients
No caffeine and no stimulants
All Natural Adaptogenic herbal formula
Servings per bottle: 30 (120 Capsules)
Satisfaction money-back guarantee
Manufactured in an FDA registered facility in the USA
Good Manufacturing Practices (GMP)
No soy, dairy, gluten, eggs, fish, shellfish, tree nuts, peanuts, or wheat

120-Day Money-Back Guarantee

We are confident you will be very happy with the results you gain from Peak Male. That’s why we offer the industry-leading 120-day satisfaction guarantee.

If for any reason you are not delighted with Peak Male, just return the unused portion or even empty bottles with your name and address within 120 days of your purchase date. Upon receipt, we will refund your purchase price, less shipping & handling within 24 hours of receiving your return (except on holidays and weekends). Refunds typically take an additional 3 to 4 business days to show on your credit card statement.

Sources & References

1. Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658772/

2. A preliminary review of studies on adaptogens: comparison of their bioactivity in TCM with that of ginseng-like herbs used worldwide https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240259/

3. G. E. Hein, M. Kohler, P. Oelzner, et al., “The advanced glycation end-product pentosidine correlates to IL-6 and other relevant inflammatory markers in rheumatoid arthritis,” Rheumatology International 26(2) (2005): 137–41.

4. A. Herold, L. Cremer, A. Calugaru, et al., “Hydroalcoholic plant extracts with anti-inflammatory activity,” Roumanian Archives of Microbiology and Immunology 62(1–2) (2003): 117–29; S. M. Choi and B. M. Lee, “An alternative mode of action of endocrine-disrupting chemicals and chemoprevention,” Journal of Toxicology and Environmental Health Part B 7(6) (2004): 451–63; J. L. Arbiser, N. Klauber, R. Rohan, et al., “Curcumin is an in vivo inhibitor of angiogenesis,” Molecular Medicine 4(6) (1998): 376–83; E. Bråkenhielm, R. Cao, and Y. Cao, “Suppression of angiogenesis, tumor growth and wound healing by resveratrol, a natural compound in red wine and grapes,” The FASEB Journal 15(10) (2001): 1798–1800; and S. Lamy, D. Gingras, and R. Beliveau, “Green tea catechins inhibit vascular endothelial growth factor receptor phosphorylation,” Cancer Research 62 (2002): 381–85.

5. Using Herbal Remedies to Maintain Optimal Weight: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927017/

6. Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protective Activity: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991026/

7. Stimulating effect of adaptogens: an overview with particular reference to their efficacy following single-dose administration.: https://www.ncbi.nlm.nih.gov/pubmed/16261511

8. Partial sleep deprivation compromises gastric mucosal integrity in rats.: https://www.ncbi.nlm.nih.gov/pubmed/15862606

9. Interrelationships between hormones and sleep.: https://www.ncbi.nlm.nih.gov/pubmed/10984255

10. Disturbed Sleep and Disturbed Bowel Functions: Implications for Constipation in Healthy Individuals: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093001/

11. Sleep quality, and behavioral factors in late reproductive-age women.: https://www.ncbi.nlm.nih.gov/pubmed/11530118

12. Sleep duration and the risk of prostate cancer: the Ohsaki Cohort Study.: https://www.ncbi.nlm.nih.gov/pubmed/18542076/

13. The relationship between sleep disorders and T in men: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955336/

14. Circadian System, Sleep and Endocrinology: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242827/

15. Chapter 26 - Endocrine Physiology in Relation to Sleep and Sleep Disturbances: https://www.sciencedirect.com/science/article/pii/B9781416066453000268

16. Short and long sleep and sleeping pills. Is increased mortality associated?: https://www.ncbi.nlm.nih.gov/pubmed/760693/

17. Sleep Duration as a Risk Factor for Cardiovascular Disease- a Review of the Recent Literature: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845795/

18. Sleep duration and quality in relation to non-alcoholic fatty liver disease in middle-aged workers and their spouses.: https://www.ncbi.nlm.nih.gov/pubmed/23578884

19. Impact of sleep debt on metabolic and endocrine function.: https://www.ncbi.nlm.nih.gov/pubmed/10543671/

20. Sleep for cognitive enhancement: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980112/

21. Sleep drives metabolite clearance from the adult brain.: https://www.ncbi.nlm.nih.gov/pubmed/24136970

22. Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313221/

23. Sleep and immune function: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256323/

24. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity.: https://www.ncbi.nlm.nih.gov/pubmed/19500070

25. Antioxidant evaluation of three adaptogen extracts.: https://www.ncbi.nlm.nih.gov/pubmed/19051347

26. Advanced glycation end products: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583887/

27. Tulsi - Ocimum sanctum: A herb for all reasons: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296439/

28. The role of nitric oxide in cardiovascular diseases.: https://www.ncbi.nlm.nih.gov/pubmed/15722114

29. Red Ginseng Extract Facilitates the Early Differentiation of Human Embryonic Cells into Mesendoderm Lineage: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949591/

30. Total extract of Korean red ginseng facilitates human bone marrow hematopoietic colony formation in vitro: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188783/

31. Raghavendran HRB, Sathyanath R, Shin J, Kim HK, Han JM, Cho J, et al. (2012) Panax ginseng Modulates Cytokines in Bone Marrow Toxicity and Myelopoiesis: Ginsenoside Rg1 Partially Supports Myelopoiesis. PLoS ONE 7(4): e33733. https://doi.org/10.1371/journal.pone.0033733

32. Korean red ginseng extract induces apoptosis and decreases telomerase activity in human leukemia cells: https://sci-hub.tw/https://www.sciencedirect.com/science/article/pii/S0378874108006314

33. Ginseng saponin metabolite suppresses phorbol ester-induced matrix metalloproteinase-9 expression through inhibition of activator protein-1 and mitogen-activated protein kinase signaling pathways in human astroglioma cells: https://sci-hub.tw/https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.21356

34. Epigenetics: The Science of Change: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1392256/

35. A ginsenoside-Rh1, a component of ginseng saponin, activates estrogen receptor in human breast carcinoma MCF-7 cells: https://sci-hub.tw/https://www.sciencedirect.com/science/article/pii/S0960076003000670

36. Anti-proliferative effect of ginseng saponins on human prostate cancer cell line: https://sci-hub.tw/https://www.sciencedirect.com/science/article/pii/S0024320500007207

37. Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling: https://sci-hub.tw/https://www.sciencedirect.com/science/article/pii/S0378874106003217

U.S. Department of Health & Human Services - National Institute of Health Scientific studies - National Library of Medicine:

Ashwagandha:

Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6979308/

Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827862/

Ashwagandha in brain disorders: A review of recent developments - https://pubmed.ncbi.nlm.nih.gov/32305638/

An overview on ashwagandha: a Rasayana (rejuvenator) of Ayurveda - https://pubmed.ncbi.nlm.nih.gov/22754076/

Natural Medicines and Their Underlying Mechanisms of Prevention and Recovery from Amyloid ?-Induced Axonal Degeneration in Alzheimer’s Disease - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369795/

Novel Methods to Generate Active Ingredients-Enriched Ashwagandha Leaves and Extracts - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147857/

Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Improving Sexual Function in Women: A Pilot Study - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609357/

Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions - https://pubmed.ncbi.nlm.nih.gov/28471731/

An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study - https://pubmed.ncbi.nlm.nih.gov/31517876/

An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750292/

Efficacy and Safety of Ashwagandha Root Extract in Subclinical Hypothyroid Patients: A Double-Blind, Randomized Placebo-Controlled Trial - https://pubmed.ncbi.nlm.nih.gov/28829155/

Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687242/

Effect of Ashwagandha Withanolides on Muscle Cell Differentiation - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533065/

Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study - https://pubmed.ncbi.nlm.nih.gov/31728244/

Effects of Withania somnifera (Ashwagandha) on Stress and the Stress- Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia - https://pubmed.ncbi.nlm.nih.gov/34254920/

Effects of eight-week supplementation of Ashwagandha on cardiorespiratory endurance in elite Indian cyclists - https://pubmed.ncbi.nlm.nih.gov/23326093/

Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462692/

Effect of an ashwagandha (Withania Somnifera) root extract on climacteric symptoms in women during perimenopause: A randomized, double-blind, placebo-controlled study - https://pubmed.ncbi.nlm.nih.gov/34553463/

Nootropic potential of Ashwagandha leaves: Beyond traditional root extracts - https://pubmed.ncbi.nlm.nih.gov/26361721/

Adaptogenic and Immunomodulatory Activity of Ashwagandha Root Extract: An Experimental Study in an Equine Model - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552885/

Glioprotective Effects of Ashwagandha Leaf Extract against Lead Induced Toxicity - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058459/

Rational use of Ashwagandha in Ayurveda (Traditional Indian Medicine) for health and healing - https://pubmed.ncbi.nlm.nih.gov/33831467/

An alternative treatment for anxiety: a systematic review of human trial results reported for the Ayurvedic herb ashwagandha (Withania somnifera) - https://pubmed.ncbi.nlm.nih.gov/25405876/

An Alternative Treatment for Anxiety: A Systematic Review of Human Trial Results Reported for the Ayurvedic Herb Ashwagandha (Withania somnifera) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270108/

Pharmacological evaluation of Ashwagandha highlighting its healthcare claims, safety, and toxicity aspects - https://pubmed.ncbi.nlm.nih.gov/32242751/

Ashwagandha root in the treatment of non-classical adrenal hyperplasia - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543599/

Ancient medicine, modern use: Withania somnifera and its potential role in integrative oncology - https://pubmed.ncbi.nlm.nih.gov/17176166/

Ashwagandha attenuates TNF-a- and LPS-induced NF-?B activation and CCL2 and CCL5 gene expression in NRK-52E cells - https://pubmed.ncbi.nlm.nih.gov/26667305/

Ashwagandha (Withania somnifera) Reverses ß-Amyloid1-42 Induced Toxicity in Human Neuronal Cells: Implications in HIV-Associated Neurocognitive Disorders (HAND) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797707/

Protective Role of Ashwagandha Leaf Extract and Its Component Withanone on Scopolamine-Induced Changes in the Brain and Brain-Derived Cells - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214041/

Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study - https://pubmed.ncbi.nlm.nih.gov/34858513/

Effects of eight-week supplementation of Ashwagandha on cardiorespiratory endurance in elite Indian cyclists - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545242/

Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632422/

Effects of Ashwagandha (Withania somnifera) on Physical Performance: Systematic Review and Bayesian Meta-Analysis - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006238/

Rhodiola:

Rhodiola rosea L.: an herb with anti-stress, anti-aging, and immunostimulating properties for cancer chemoprevention - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208354/

Rhodiola rosea for physical and mental fatigue: a systematic review - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541197/

Rhodiola rosea: a possible plant adaptogen - https://pubmed.ncbi.nlm.nih.gov/11410073/

Stress management and the role of Rhodiola rosea: a review - https://pubmed.ncbi.nlm.nih.gov/29325481/

Rhodiola rosea therapy for major depressive disorder: a study protocol for a randomized, double-blind, placebo- controlled trial - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297663/

The Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood Symptoms - https://pubmed.ncbi.nlm.nih.gov/26502953/

Effects of Rhodiola rosea supplementation on mental performance, physical capacity, and oxidative stress biomarkers in healthy men - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230218/

The interaction of Rhodiola rosea and antidepressants. A case report - https://pubmed.ncbi.nlm.nih.gov/25413939/

Rhodiola rosea L. as a putative botanical antidepressant - https://pubmed.ncbi.nlm.nih.gov/27013349/

Mixing ratio optimization for functional complex extracts of Rhodiola crenulata, Panax quinquefolius, and Astragalus membranaceus using mixture design and verification of immune functional efficacy in animal models - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105012/

Rhodiola rosea L. Improves Learning and Memory Function: Preclinical Evidence and Possible Mechanisms - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288277/

Phytochemical, Antibacterial and Antioxidant Activity Evaluation of Rhodiola crenulata - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464835/

Adjunctive Treatment with Rhodiola Crenulata in Patients with Chronic Obstructive Pulmonary Disease – A Randomized Placebo Controlled Double Blind Clinical Trial - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476627/

Rhodiola: a promising anti-aging Chinese herb - https://pubmed.ncbi.nlm.nih.gov/17990971/

A pilot study of Rhodiola rosea (Rhodax) for generalized anxiety disorder (GAD) - https://pubmed.ncbi.nlm.nih.gov/18307390/

The effect of in vitro gastrointestinal digestion on the phenolic profiles, bioactivities and bioaccessibility of Rhodiola - https://pubmed.ncbi.nlm.nih.gov/35532981/

Rosenroot (Rhodiola): Potential Applications in Aging-related Diseases - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345333/

Anti-inflammatory activity of Rhodiola rosea - a second-generation adaptogen - https://pubmed.ncbi.nlm.nih.gov/19152369/

Rhodiola rosea for physical and mental fatigue: a systematic review - https://pubmed.ncbi.nlm.nih.gov/22643043/

Antioxidant and Antibacterial Activity of Roseroot (Rhodiola rosea L.) Dry Extracts - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099734/

Rhodiola rosea versus sertraline for major depressive disorder: A randomized placebo-controlled trial - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385215/

Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial - https://pubmed.ncbi.nlm.nih.gov/28219059/

Rhodiola rosea versus sertraline for major depressive disorder: A randomized placebo-controlled trial - https://pubmed.ncbi.nlm.nih.gov/25837277/

Rhodiola and salidroside in the treatment of metabolic disorders - https://pubmed.ncbi.nlm.nih.gov/31481002/

Rhodiola crenulata reduces ventricular arrhythmia through mitigating the activation of IL-17 and inhibiting the MAPK signaling pathway - https://pubmed.ncbi.nlm.nih.gov/32946036/

Monoamine oxidase inhibition by Rhodiola rosea L. roots - https://pubmed.ncbi.nlm.nih.gov/19168123/

Neuroprotective Effects of Rhodiola Sacra on Transient Global Cerebral Ischemia Through Activating AMPK/Nrf2 Pathway in Rats - https://pubmed.ncbi.nlm.nih.gov/34714119/

The effect of rhodiola and acetazolamide on the sleep architecture and blood oxygen saturation in men living at high altitude - https://pubmed.ncbi.nlm.nih.gov/12423559/

Rhodiola extract promotes longevity and stress resistance of Caenorhabditis elegans via DAF-16 and SKN-1 - https://pubmed.ncbi.nlm.nih.gov/33881421/

Rhodiola rosea: A Versatile Adaptogen - https://pubmed.ncbi.nlm.nih.gov/33430554/

Rhodiola rosea L.: an herb with anti-stress, anti-aging, and immunostimulating properties for cancer chemoprevention - https://pubmed.ncbi.nlm.nih.gov/30393593/

Antioxidant and Antibacterial Activity of Roseroot (Rhodiola rosea L.) Dry Extracts - https://pubmed.ncbi.nlm.nih.gov/30022015/

The efficacy and safety of Chinese herbal medicine, Rhodiola formulation in treating ischemic heart disease: a systematic review and meta-analysis of randomized controlled trials - https://pubmed.ncbi.nlm.nih.gov/25146085/

Antihyperglycemic action of rhodiola-aqeous extract in type1-like diabetic rats - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897963/

Pharmacological activities, mechanisms of action, and safety of salidroside in the central nervous system - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973445/

Mechanism of action of Rhodiola, salidroside, tyrosol and triandrin in isolated neuroglial cells: an interactive pathway analysis of the downstream effects using RNA microarray data - https://pubmed.ncbi.nlm.nih.gov/25172797/

Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression - https://pubmed.ncbi.nlm.nih.gov/17990195/

The Adaptogens Rhodiola and Schizandra Modify the Response to Immobilization Stress in Rabbits by Suppressing the Increase of Phosphorylated Stress-activated Protein Kinase, Nitric Oxide and Cortisol - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155223/

Rhodiola rosea L. Attenuates Cigarette Smoke and Lipopolysaccharide-Induced COPD in Rats via Inflammation Inhibition and Antioxidant and Antifibrosis Pathways - https://pubmed.ncbi.nlm.nih.gov/33747104/

Rhodiola rosea Exerts Antiviral Activity in Athletes Following a Competitive Marathon Race - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521101/

Rhodiola/Cordyceps-Based Herbal Supplement Promotes Endurance Training-Improved Body Composition But Not Oxidative Stress and Metabolic Biomarkers: A Preliminary Randomized Controlled Study - https://pubmed.ncbi.nlm.nih.gov/31623349/

The effects of Rhodiola rosea extract on 5-HT level, cell proliferation and quantity of neurons at cerebral hippocampus of depressive rats - https://pubmed.ncbi.nlm.nih.gov/19403286/

Beneficial Effects of Rhodiola and Salidroside in Diabetes: Potential Role of AMP-Activated Protein Kinase - https://pubmed.ncbi.nlm.nih.gov/31069710/

Rhodiola rosea suppresses thymus T-lymphocyte apoptosis by downregulating tumor necrosis factor-a-induced protein 8-like-2 in septic rats - https://pubmed.ncbi.nlm.nih.gov/26063084/

Anti-inflammatory effects of Rhodiola rosea L.: A review - https://pubmed.ncbi.nlm.nih.gov/31715370/

Effects of rhodiola rosea on oxidative stress and negative emotional states in patients with obstructive sleep apnea - https://pubmed.ncbi.nlm.nih.gov/31623042/

Rhodiola rosea: A Therapeutic Candidate on Cardiovascular Diseases - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898776/

Schisandra:

A randomized, double-blind, placebo-controlled trial of Schisandra chinensis for menopausal symptoms - https://pubmed.ncbi.nlm.nih.gov/27763802/

Current knowledge of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine) as a medicinal plant species: a review on the bioactive components, pharmacological properties, analytical and biotechnological studies - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378736/

The effect of Schisandra chinensis extracts on depression by noradrenergic, dopaminergic, GABAergic and glutamatergic systems in the forced swim test in mice - https://pubmed.ncbi.nlm.nih.gov/27225351/

Potential of Schisandra chinensis (Turcz.) Baill. in Human Health and Nutrition: A Review of Current Knowledge and Therapeutic Perspectives - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412213/

Antioxidant Effects of Schisandra chinensis Fruits and Their Active Constituents - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073495/

Schisandra chinensis Fructus and Its Active Ingredients as Promising Resources for the Treatment of Neurological Diseases - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073455/

Pharmacology of Schisandra chinensis Bail.: an overview of Russian research and uses in medicine - https://pubmed.ncbi.nlm.nih.gov/18515024/

Effect of Schisandra chinensis Extract Supplementation on Quadriceps Muscle Strength and Fatigue in Adult Women: A Randomized, Double-Blind, Placebo-Controlled Trial - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177795/

Relaxation Effect of Schisandra Chinensis Lignans on the Isolated Tracheal Smooth Muscle in Rats and Its Mechanism - https://pubmed.ncbi.nlm.nih.gov/34406878/

Preventive Effects of Schisandrin A, A Bioactive Component of Schisandra chinensis, on Dexamethasone-Induced Muscle Atrophy - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282012/

Deoxyschizandrin, Isolated from Schisandra Berries, Induces Cell Cycle Arrest in Ovarian Cancer Cells and Inhibits the Protumoural Activation of Tumour-Associated Macrophages - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793319/

Pathological observations of Fructus Schisandrae polysaccharide on anti-tumor effects in S180-bearing mice - https://pubmed.ncbi.nlm.nih.gov/15272786/

Effects of Selenylation Modification on Antioxidative Activities of Schisandra chinensis Polysaccharide - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521803/

Neuroprotective Effect of Schisandra Chinensis on Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Parkinsonian Syndrome in C57BL/6 Mice - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683275/

Schisandra Inhibit Bleomycin-Induced Idiopathic Pulmonary Fibrosis in Rats via Suppressing M2 Macrophage Polarization - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455820/

Schisandra chinensis fruit extract attenuates albuminuria and protects podocyte integrity in a mouse model of streptozotocin-induced diabetic nephropathy - https://pubmed.ncbi.nlm.nih.gov/22353431/

Effects of Schisandra chinensis extracts on cough and pulmonary inflammation in a cough hypersensitivity guinea pig model induced by cigarette smoke exposure - https://pubmed.ncbi.nlm.nih.gov/25681545/

Research progress in application and mechanism of Schisandrae Chinensis Fructus for prevention and treatment of liver diseases - https://pubmed.ncbi.nlm.nih.gov/32893568/

The Anti-colitis Effect of Schisandra chinensis Polysaccharide Is Associated With the Regulation of the Composition and Metabolism of Gut Microbiota - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609416/

Schisandra sphenanthera Extract Facilitates Liver Regeneration after Partial Hepatectomy in Mice - https://pubmed.ncbi.nlm.nih.gov/26932815/

Chemical constituents from Schisandra sphenanthera and their cytotoxic activity - https://pubmed.ncbi.nlm.nih.gov/31829042/

Characterization of the Omija ( Schisandra chinensis) Extract and Its Effects on the Bovine Sperm Vitality and Oxidative Profile during In Vitro Storage - https://pubmed.ncbi.nlm.nih.gov/33029171/

Schisandra polysaccharide evokes immunomodulatory activity through TLR 4-mediated activation of macrophages - https://pubmed.ncbi.nlm.nih.gov/24418335/

Effects of schizandrol A on monoamine neurotransmitters in the central nervous system - https://pubmed.ncbi.nlm.nih.gov/1678991/

Schizandrin A can inhibit non-small cell lung cancer cell proliferation by inducing cell cycle arrest, apoptosis and autophagy - https://pubmed.ncbi.nlm.nih.gov/34643254/

Schisandra chinensis ameliorates depressive-like behaviors by regulating microbiota-gut-brain axis via its anti-inflammation activity - https://pubmed.ncbi.nlm.nih.gov/32761702/

Schisandra chinensis extract ameliorates nonalcoholic fatty liver via inhibition of endoplasmic reticulum stress - https://pubmed.ncbi.nlm.nih.gov/26972505/

Evaluation of the protective effects of Schisandra chinensis on Phase I drug metabolism using a CCl4 intoxication model - https://pubmed.ncbi.nlm.nih.gov/10616961/

Schisandrol B Protects Against Acetaminophen-Induced Hepatotoxicity by Inhibition of CYP-Mediated Bioactivation and Regulation of Liver Regeneration - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334815/

Promotion effect of Schisandra nigra on the growth of hair - https://pubmed.ncbi.nlm.nih.gov/19153064/

A review of polysaccharides from Schisandra chinensis and Schisandra sphenanthera: Properties, functions and applications - https://pubmed.ncbi.nlm.nih.gov/29352909/

Current knowledge of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine) as a medicinal plant species: a review on the bioactive components, pharmacological properties, analytical and biotechnological studies - https://pubmed.ncbi.nlm.nih.gov/28424569/

Potential of Schisandra chinensis (Turcz.) Baill. in Human Health and Nutrition: A Review of Current Knowledge and Therapeutic Perspectives - https://pubmed.ncbi.nlm.nih.gov/30720717/

Schisandra Chinensis Lignans Suppresses the Production of Inflammatory Mediators Regulated by NF-?B, AP-1, and IRF3 in Lipopolysaccharide-Stimulated RAW264.7 Cells - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320760/

Schisandra chinensis produces the antidepressant-like effects in repeated corticosterone-induced mice via the BDNF/TrkB/CREB signaling pathway - https://pubmed.ncbi.nlm.nih.gov/27387555/

Study on the Hepatoprotection of Schisandra chinensis Caulis Polysaccharides in Nonalcoholic Fatty Liver Disease in Rats Based on Metabolomics - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490749/

Anti-Cancer Effects of a-Cubebenoate Derived from Schisandra chinensis in CT26 Colon Cancer Cells - https://pubmed.ncbi.nlm.nih.gov/35164001/

Schisandra chinensis Baill, a Chinese medicinal herb, alleviates high-fat-diet-inducing non-alcoholic steatohepatitis in rats - https://pubmed.ncbi.nlm.nih.gov/24653581/

Schisandra chinensis polysaccharides prevent cardiac hypertrophy by dissociating thioredoxin-interacting protein/thioredoxin-1 complex and inhibiting oxidative stress - https://pubmed.ncbi.nlm.nih.gov/34243612/

Schisandra chinensis prevents alcohol-induced fatty liver disease - https://pubmed.ncbi.nlm.nih.gov/24456360/

Chemical composition analysis of Schisandra chinensis fructus and its three processed products using UHPLC-Q-Orbitrap/MS-based metabolomics approach - https://pubmed.ncbi.nlm.nih.gov/33297729/

A randomized, double-blind, placebo-controlled trial of Schisandra chinensis for menopausal symptoms - https://pubmed.ncbi.nlm.nih.gov/27763802/

Schisandra Extract and Ascorbic Acid Synergistically Enhance Cognition in Mice Through Modulation of Mitochondrial Respiration - https://pubmed.ncbi.nlm.nih.gov/32218327/

Ameliorative effects of Schizandra chinensis on osteoporosis via activation of estrogen receptor (ER)-a/-ß - https://pubmed.ncbi.nlm.nih.gov/24881676/

Identification and characterization of potent CYP3A4 inhibitors in Schisandra fruit extract - https://pubmed.ncbi.nlm.nih.gov/15342469/

Targeted Lignan Profiling and Anti-Inflammatory Properties of Schisandra rubriflora and Schisandra chinensis Extracts - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321394/

Schisandra chinensis acidic polysaccharide partialy reverses acetaminophen-induced liver injury in mice - https://pubmed.ncbi.nlm.nih.gov/31400930/

Phytochemical and biotechnological studies on Schisandra chinensis cultivar Sadova No. 1—a high utility medicinal plant - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959991/

Relaxant effects of Schisandra chinensis and its major lignans on agonists-induced contraction in ileum - https://pubmed.ncbi.nlm.nih.gov/21764275/

Schisandra sphenanthera extract (Wuzhi Tablet) protects against chronic-binge and acute alcohol-induced liver injury by regulating the NRF2-ARE pathway - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595297/

Inhibitory Effects of Schisandra Lignans on Cytochrome P450s and Uridine 5'-Diphospho-Glucuronosyl Transferases in Human Liver Microsomes - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000448/

Effects of Lignans from Schisandra chinensis Rattan Stems against Aß1-42-Induced Memory Impairment in Rats and Neurotoxicity in Primary Neuronal Cells - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017482/

Deoxyschizandrin, Isolated from Schisandra Berries, Induces Cell Cycle Arrest in Ovarian Cancer Cells and Inhibits the Protumoural Activation of Tumour-Associated Macrophages - https://pubmed.ncbi.nlm.nih.gov/29342940/

Schisandra chinensis and Its Main Constituent Schizandrin Attenuate Allergic Reactions by Down-Regulating Caspase-1 - https://pubmed.ncbi.nlm.nih.gov/28081628/

Lignans from Schisandra sphenanthera protect against lithocholic acid-induced cholestasis by pregnane X receptor activation - https://pubmed.ncbi.nlm.nih.gov/31336134/

Pharmacokinetic and nephroprotective benefits of using Schisandra chinensis extracts in a cyclosporine A-based immune-suppressive regime - https://pubmed.ncbi.nlm.nih.gov/26355803/

Schisandra chinensis extract ameliorates age-related muscle wasting and bone loss - https://pubmed.ncbi.nlm.nih.gov/31074579/

A Schisandra-Derived Compound Schizandronic Acid Inhibits Entry of Pan-HCV Genotypes into Human Hepatocytes - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890123/

Schizandrin, an antioxidant lignan from Schisandra chinensis, ameliorates Aß1-42-induced memory impairment - https://pubmed.ncbi.nlm.nih.gov/22829961/

Schisandra Chinensis Acidic Polysaccharide Improves the Insulin Resistance in Type 2 Diabetic Rats by Inhibiting Inflammation - https://pubmed.ncbi.nlm.nih.gov/32181695/

Prevention effects of Schisandra polysaccharide on radiation-induced immune system dysfunction - https://pubmed.ncbi.nlm.nih.gov/25709011/

Protective effects of gomisin A isolated from Schisandra chinensis against CCl(4)-induced hepatic and renal injury - https://pubmed.ncbi.nlm.nih.gov/23381504/

Clinical observation of the effect of modified Ginseng-Schisandra decoction (MGSD) on trace elements and immune function in children with spleen deficiency syndrome after recurrent respiratory tract infection (RRTI): a randomized controlled trial - https://pubmed.ncbi.nlm.nih.gov/34295784/

Medicinal Plants as a Potential and Successful Treatment Option in the Context of Atherosclerosis - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156611/

Panax ginseng, Rhodiola rosea and Schisandra chinensis - https://pubmed.ncbi.nlm.nih.gov/22039930/

Plant Adaptogens - History and Future Perspectives - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398443/

Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid-Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration - https://pubmed.ncbi.nlm.nih.gov/26658429/

An overview of neuroprotective and cognitive enhancement properties of lignans from Schisandra chinensis - https://pubmed.ncbi.nlm.nih.gov/29136774/

Growth inhibition and cell cycle arrest in the G0/G1 by schizandrin, a dibenzocyclooctadiene lignan isolated from Schisandra chinensis, on T47D human breast cancer cells - https://pubmed.ncbi.nlm.nih.gov/19585470/

Evaluation of cytotoxic activity of Schisandra chinensis lignans - https://pubmed.ncbi.nlm.nih.gov/20458670/

Antidepressant-like effects and cognitive enhancement of Schisandra chinensis in chronic unpredictable mild stress mice and its related mechanism - https://pubmed.ncbi.nlm.nih.gov/28761074/

Phytochemical and biotechnological studies on Schisandra chinensis cultivar Sadova No. 1-a high utility medicinal plant - https://pubmed.ncbi.nlm.nih.gov/29687144/

Ginseng:

Effects of American ginseng (Panax quinquefolius) on neurocognitive function: an acute, randomised, double-blind, placebo-controlled, crossover study - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952762/

Mechanisms of Panax ginseng action as an antidepressant - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6869450/

Ginseng and Ginkgo Biloba Effects on Cognition as Modulated by Cardiovascular Reactivity: A Randomised Trial - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777384/

Metabolome and gut microbiota variation with long-term intake of Panax ginseng extracts - https://pubmed.ncbi.nlm.nih.gov/29896600/

Effects of ginseng on stress-related depression, anxiety, and the hypothalamic-pituitary-adrenal axis - https://pubmed.ncbi.nlm.nih.gov/29021708/

Ginseng berry concentrate prevents colon cancer via cell cycle and apoptosis regulation, and inflammation-linked Th17 cell differentiation - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363175/

Ginseng for Treating Hypertension: A Systematic Review and Meta-Analysis of Double Blind, Randomized, Placebo-Controlled Trials - https://pubmed.ncbi.nlm.nih.gov/28707603/

Ginseng consumption and risk of cancer: A meta-analysis - https://pubmed.ncbi.nlm.nih.gov/27616903/

Ginseng on Hyperglycemia: Effects and Mechanisms - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781779/

Effects of Panax ginseng and ginsenosides on oxidative stress and cardiovascular diseases: pharmacological and therapeutic roles - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753520/

Possibility as role of ginseng and ginsenosides on inhibiting the heart disease of COVID-19: A systematic review - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767974/

Ginseng, the 'Immunity Boost': The Effects of Panax ginseng on Immune System - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659612/

Red ginseng for treating erectile dysfunction: a systematic review - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561113/

Ginseng in Traditional Herbal Prescriptions - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659587/

Ginseng for managing menopausal woman's health - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044908/

Ginseng as a Treatment for Fatigue: A Systematic Review - https://pubmed.ncbi.nlm.nih.gov/29624410/

Effects of Ginseng Ingestion on Salivary Testosterone and DHEA Levels in Healthy Females: An Exploratory Study - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352699/

An Open-Label, Pilot Trial of Red Ginseng in Chronic Fatigue Syndrome, Fibromyalgia, and Post-Viral Fatigue - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777686/

Antioxidant, Anti-Inflammatory and Antithrombotic Effects of Ginsenoside Compound K Enriched Extract Derived from Ginseng Sprouts - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272189/

Beneficial effects of Panax ginseng for the treatment and prevention of neurodegenerative diseases - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035378/

The effect of ginseng (genus Panax) on blood pressure: a systematic review and meta-analysis of randomized controlled clinical trials - https://pubmed.ncbi.nlm.nih.gov/27074879/

Ginseng for health care: a systematic review of randomized controlled trials in Korean literature - https://pubmed.ncbi.nlm.nih.gov/23560064/

Therapeutic potential of Panax ginseng and ginsenosides in the treatment of chronic obstructive pulmonary disease - https://pubmed.ncbi.nlm.nih.gov/25440386/

Effects of red ginseng extract on sleeping behaviors in human volunteers - https://pubmed.ncbi.nlm.nih.gov/23872254/

Ginseng (Panax quinquefolius) to improve cancer-related fatigue: a randomized, double-blind trial, N07C2 - https://pubmed.ncbi.nlm.nih.gov/23853057/

A comparison of the ancient use of ginseng in traditional Chinese medicine with modern pharmacological experiments and clinical trials - https://pubmed.ncbi.nlm.nih.gov/18567057/

Adaptogenic effects of Panax ginseng on modulation of cardiovascular functions - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322748/

Ginseng alleviates cyclophosphamide-induced hepatotoxicity via reversing disordered homeostasis of glutathione and bile acid - https://pubmed.ncbi.nlm.nih.gov/26625948/

Panax ginseng: a candidate herbal medicine for autoimmune disease - https://pubmed.ncbi.nlm.nih.gov/31308804/

Ginseng in the treatment of fatigue in multiple sclerosis: a randomized, placebo-controlled, double-blind pilot study - https://pubmed.ncbi.nlm.nih.gov/23301896/

American ginseng suppresses inflammation and DNA damage associated with mouse colitis - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639244/

Panax ginseng and its ginsenosides: potential candidates for the prevention and treatment of chemotherapy-induced side effects - https://pubmed.ncbi.nlm.nih.gov/34764717/

Ginseng Protein Reverses Amyloid Beta Peptide and H 2 O 2 Cytotoxicity in Neurons, and Ameliorates Cognitive Impairment in AD Rats Induced by a Combination of D-Galactose and AlCl3 - https://pubmed.ncbi.nlm.nih.gov/27981642/

Protective effects of ginseng on neurological disorders - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503934/

Efficacy comparison of Korean ginseng and American ginseng on body temperature and metabolic parameters - https://pubmed.ncbi.nlm.nih.gov/24467543/

A comprehensive review of the therapeutic and pharmacological effects of ginseng and ginsenosides in central nervous system - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659622/

Pharmacological potential of ginseng and its major component ginsenosides - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020288/

A review on the medicinal potentials of ginseng and ginsenosides on cardiovascular diseases - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213864/

Effects of Ginseng on Neurological Disorders - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099600/

Ginseng, the natural effectual antiviral: Protective effects of Korean Red Ginseng against viral infection - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052424/

Protective roles of ginseng against bacterial infection - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244293/

Red ginseng monograph - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190493/

Red Ginseng Extract Promotes the Hair Growth in Cultured Human Hair Follicles - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350143/

The effect of ginseng on sexual dysfunction in menopausal women: A double-blind, randomized, controlled trial - https://pubmed.ncbi.nlm.nih.gov/31331583/

Adaptogenic effects of Panax ginseng on modulation of immune functions - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790873/

An Open-Label, Pilot Trial of Red Ginseng in Chronic Fatigue Syndrome, Fibromyalgia, and Post-Viral Fatigue - https://pubmed.ncbi.nlm.nih.gov/35056100/

American ginseng suppresses inflammation and DNA damage associated with mouse colitis - https://pubmed.ncbi.nlm.nih.gov/18802031/

Ginseng for managing menopausal woman's health: A systematic review of double-blind, randomized, placebo-controlled trials - https://pubmed.ncbi.nlm.nih.gov/27661038/

Ginseng and Cancer-Related Fatigue: A Systematic Review of Clinical Trials - https://pubmed.ncbi.nlm.nih.gov/32691627/

Ginseng alleviates microbial infections of the respiratory tract - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031735/

Ginseng Compounds: An Update on Their Molecular Mechanisms and Medical Applications - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928028/

Actoprotective effect of ginseng: improving mental and physical performance - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659633/

Effects of Korean White Ginseng (Panax Ginseng C.A. Meyer) on Vascular and Glycemic Health in Type 2 Diabetes: Results of a Randomized, Double Blind, Placebo-controlled, Multiple-crossover, Acute Dose Escalation Trial - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135246/

Effects of Korean Red Ginseng on Cognitive and Motor Function: A Double-blind, Randomized, Placebo-controlled Trial - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659585/

Pharmacological Efficacy of Ginseng against Respiratory Tract Infections - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271507/

Hair-Growth Potential of Ginseng and Its Major Metabolites: A Review on Its Molecular Mechanisms - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163201/

Efficacy of Ginseng Supplements on Fatigue and Physical Performance: a Meta-analysis - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102849/

Effects of ginseng on stress-related depression, anxiety, and the hypothalamic–pituitary–adrenal axis - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628357/

Ginseng: An Nonnegligible Natural Remedy for Healthy Aging - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758347/

Ginseng for Improving Semen Quality Parameters: A Systematic Review - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308228/

The effect of red ginseng and ginseng leaves on the substance and energy metabolism in hypothyroidism - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628355/

Ginseng and male reproductive function - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861174/

Bioconversion, health benefits, and application of ginseng and red ginseng in dairy products - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049797/

Biological Activities of Ginseng and Its Application to Human Health - https://www.ncbi.nlm.nih.gov/books/NBK92776/

Red Ginseng Supplementation More Effectively Alleviates Psychological than Physical Fatigue - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659534/

Functional role of ginseng-derived compounds in cancer - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026353/

Effects of ginseng on two main sex steroid hormone receptors: estrogen and androgen receptors - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386121/

Ginseng and diabetes - https://pubmed.ncbi.nlm.nih.gov/16047557/

Role of ginseng in the neurovascular unit of neuroinflammatory diseases focused on the blood-brain barrier - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587512/

Panax ginseng therapy for chronic obstructive pulmonary disease: a clinical trial protocol and pilot study - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144315/

Red Ginseng Extract Reduced Metastasis of Colon Cancer Cells In Vitro and In Vivo - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659544/

Pro-Resolving Effect of Ginsenosides as an Anti-Inflammatory Mechanism of Panax ginseng - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175368/

The Effect of Ginseng (The Genus Panax) on Glycemic Control: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180277/

The Effect of a 2-Week Red Ginseng Supplementation on Food Efficiency and Energy Metabolism - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352690/

Panax ginseng and aging related disorders: A systematic review - https://pubmed.ncbi.nlm.nih.gov/35143871/

Pharmacological and medical applications of Panax ginseng and ginsenosides: a review for use in cardiovascular diseases - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026386/

Ginseng polysaccharides: A potential neuroprotective agent - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020291/

Ginseng for an eye: effects of ginseng on ocular diseases - https://pubmed.ncbi.nlm.nih.gov/32095091/

Panax Ginseng alleviates thioacetamide-induced liver injury in ovariectomized rats: Crosstalk between inflammation and oxidative stress - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629276/

Potential Role of Ginseng in the Treatment of Colorectal Cancer - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676850/

The effects of Panax ginseng on quality of life - https://pubmed.ncbi.nlm.nih.gov/12605613/

The Efficacy of Ginseng-Related Therapies in Type 2 Diabetes Mellitus: An Updated Systematic Review and Meta-analysis - https://pubmed.ncbi.nlm.nih.gov/26871778/

Red ginseng oil promotes hair growth and protects skin against UVC radiation - https://pubmed.ncbi.nlm.nih.gov/34295210/

Red ginseng for treating erectile dysfunction: a systematic review - https://www.ncbi.nlm.nih.gov/books/NBK76277/

The Effects of a Korean Ginseng, GINST15, on Perceptual Effort, Psychomotor Performance, and Physical Performance in Men and Women - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844213/

The Difference between White and Red Ginseng: Variations in Ginsenosides and Immunomodulation - https://pubmed.ncbi.nlm.nih.gov/29925101/

Ginseng and Diabetes: The Evidences from In Vitro, Animal and Human Studies - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659569/

Chronic dietary ginseng extract administration ameliorates antioxidant and cholinergic systems in the brains of aged mice - https://pubmed.ncbi.nlm.nih.gov/29021712/

Panax ginseng: a role in cancer therapy - https://pubmed.ncbi.nlm.nih.gov/12941165/

Effects of fermented ginseng on the gut microbiota and immunity of rats with antibiotic-associated diarrhea - https://pubmed.ncbi.nlm.nih.gov/33217518/

Comparative Study of Korean White, Red, and Black Ginseng Extract on Cholinesterase Inhibitory Activity and Cholinergic Function - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659552/

Panax ginseng: a candidate herbal medicine for autoimmune disease - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606836/

A comprehensive review on the phytochemistry, pharmacokinetics, and antidiabetic effect of Ginseng - https://pubmed.ncbi.nlm.nih.gov/34583224/

Eleuthero:

The effect of eight weeks of supplementation with Eleutherococcus senticosus on endurance capacity and metabolism in human - https://pubmed.ncbi.nlm.nih.gov/21793317/

Effects of Siberian ginseng (Eleutherococcus senticosus maxim.) on elderly quality of life: a randomized clinical trial - https://pubmed.ncbi.nlm.nih.gov/15207399/

The Role of Adaptogens in Prophylaxis and Treatment of Viral Respiratory Infections - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558817/

Eleutheroside E, An Active Component of Eleutherococcus senticosus, Ameliorates Insulin Resistance in Type 2 Diabetic db/db Mice - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638629/

Memory Enhancement by Oral Administration of Extract of Eleutherococcus senticosus Leaves and Active Compounds Transferred in the Brain - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567285/

Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity - https://pubmed.ncbi.nlm.nih.gov/19500070/

Vascular effects of Siberian ginseng (Eleutherococcus senticosus): endothelium-dependent NO- and EDHF-mediated relaxation depending on vessel size - https://pubmed.ncbi.nlm.nih.gov/15095033/

Flow-cytometric studies with eleutherococcus senticosus extract as an immunomodulatory agent - https://pubmed.ncbi.nlm.nih.gov/2963645/

Assessment of the effects of eleutherococcus senticosus on endurance performance - https://pubmed.ncbi.nlm.nih.gov/15902991/

Siberian ginseng (Eleutheroccus senticosus) effects on CYP2D6 and CYP3A4 activity in normal volunteers - https://pubmed.ncbi.nlm.nih.gov/12695337/

Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protective Activity - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991026/

Eleutheroside B or E enhances learning and memory in experimentally aged rats - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145894/

Anti-depressant effects of aqueous extract from Acanthopanax senticosus in mice - https://pubmed.ncbi.nlm.nih.gov/23418105/

The influence of active components of Eleutherococcus senticosus on cellular defence and physical fitness in man - https://pubmed.ncbi.nlm.nih.gov/10641044/

Acanthopanax senticosus: review of botany, chemistry and pharmacology - https://pubmed.ncbi.nlm.nih.gov/21434569/

Eleutherococcus senticosus extract attenuates LPS-induced iNOS expression through the inhibition of Akt and JNK pathways in murine macrophage - https://pubmed.ncbi.nlm.nih.gov/17644291/

Effects of polysaccharide-enriched Acanthopanax senticosus extract on growth performance, immune function, antioxidation, and ileal microbial populations in broiler chickens - https://pubmed.ncbi.nlm.nih.gov/33647719/

Inhibitory effects of mast cell-mediated allergic reactions by cell cultured Siberian Ginseng - https://pubmed.ncbi.nlm.nih.gov/11322643/

Drug-Induced Liver Toxicity and Prevention by Herbal Antioxidants: An Overview - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726750/

LC-ESI-MS/MS profiling of phenolics from Eleutherococcus spp. inflorescences, structure-activity relationship as antioxidants, inhibitors of hyaluronidase and acetylcholinesterase - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506723/

Development of a highly reproducible system to evaluate inhibition of cytochrome P450 3A4 activity by natural medicines - https://pubmed.ncbi.nlm.nih.gov/26626238/

A preliminary review of studies on adaptogens: comparison of their bioactivity in TCM with that of ginseng-like herbs used worldwide - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240259/

Siberian ginseng reduces infarct volume in transient focal cerebral ischaemia in Sprague-Dawley rats - https://pubmed.ncbi.nlm.nih.gov/15852490/

Effect of Asian and Siberian ginseng on serum digoxin measurement by five digoxin immunoassays. Significant variation in digoxin-like immunoreactivity among commercial ginsengs - https://pubmed.ncbi.nlm.nih.gov/12580002/

Acanthopanax senticosus: Photochemistry and Anticancer Potential - https://pubmed.ncbi.nlm.nih.gov/27852123/

Phytochemical Content and Pharma-Nutrition Study on Eleutherococcus senticosus Fruits Intractum - https://www.ncbi.nlm .nih.gov/pmc/articles/PMC5098108/

Preventive Effects of Eleutherococcus senticosus Bark Extract in OVX-Induced Osteoporosis in Rats - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269741/

Effect of Asian ginseng, Siberian ginseng, and Indian ayurvedic medicine Ashwagandha on serum digoxin measurement by Digoxin III, a new digoxin immunoassay - https://pubmed.ncbi.nlm.nih.gov/18623124/

Randomized controlled trial of Siberian ginseng for chronic fatigue - https://pubmed.ncbi.nlm.nih.gov/14971626/

Ginseng for the Treatment of Chronic Fatigue Syndrome: A Systematic Review of Clinical Studies - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848096/

Antiedema effects of Siberian ginseng in humans and its molecular mechanism of lymphatic vascular function in vitro - https://pubmed.ncbi.nlm.nih.gov/27333960/

Asian and Siberian ginseng as a potential modulator of immune function: an in vitro cytokine study using mouse macrophages - https://pubmed.ncbi.nlm.nih.gov/12482627/

Cytochrome P450 enzyme mediated herbal drug interactions - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464477/

Adaptogens: the Stunning Soviet Discovery

Adaptogens are ancient, natural herbs that come from a highly-researched specific type of plant that has developed properties to:

Adapt to the most extreme, harsh, and stressful environments on earth.

When ingested, scientists have discovered that these adaptogenic herbs pass their amazing ability to adapt to and overcome stress.
Adaptogens were used in ancient Chinese medicine by Viking Warriors, Siberian hunters, and other cultures to increase energy, strength, and mental and physical endurance before going on dangerous hunts, into battle, or on long, arduous journeys.1, *
Adaptogens have also been used for centuries as a healer by many different Asian cultures who discovered they strengthen the body’s resistance to disease and have anti-fatigue, anti-anxiety, anti-inflammatory, anti-depression, and anti-aging characteristics.2, *
In modern times, these herbs were rediscovered by Soviet scientists and given to their Olympic athletes, astronauts, elite soldiers, and even World Champion chess players because of their amazing ability to reduce stress and strengthen immunity coupled with their extraordinary physical and mental performance-boosting properties.

For more information about the modern use of adaptogens, go here: The Amazing Russian Discovery.

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